PEGylated curcumin-loaded nanofibrous mats with controlled burst release through bead knot-on-spring design
نویسندگان
چکیده
منابع مشابه
Hydrophobic Drug-Loaded PEGylated Magnetic Liposomes for Drug-Controlled Release
Less targeted and limited solubility of hydrophobic-based drug are one of the serious obstacles in drug delivery system. Thus, new strategies to enhance the solubility of hydrophobic drug and controlled release behaviors would be developed. Herein, curcumin, a model of hydrophobic drug, has been loaded into PEGylated magnetic liposomes as a drug carrier platform for drug controlled release syst...
متن کاملPreparation of antibacterial electrospun Poly lactic-co–glycolic acid nanofibers containing Hypericum Perforatum with bedsore healing property and evaluation of its drug release performance
Skin drug delivery systems with controlled release are suitable means for the local transfer of pharmaceutical compounds to the damaged and healthy layers of skin. Nanofibrous membrane prepares uniform moisture in the wound environment with less accumulation of fluid secretion due to its variable pore size. Electrospinning takes advantage of using herbal extracts in the form of electrospun nano...
متن کاملPreparation of antibacterial electrospun Poly lactic-co–glycolic acid nanofibers containing Hypericum Perforatum with bedsore healing property and evaluation of its drug release performance
Skin drug delivery systems with controlled release are suitable means for the local transfer of pharmaceutical compounds to the damaged and healthy layers of skin. Nanofibrous membrane prepares uniform moisture in the wound environment with less accumulation of fluid secretion due to its variable pore size. Electrospinning takes advantage of using herbal extracts in the form of electrospun nano...
متن کاملSustained release Curcumin loaded Solid Lipid Nanoparticles.
PURPOSE curcumin is poorly water soluble drug with low bioavailability. Use of lipid systems in lipophilic substances increases solubility and bioavailability of poorly soluble drugs. The aim of this study was to prepare curcumin loaded Solid Lipid Nanoparticles (SLNs) with high loading efficiency, small particle size and prolonged release profile with enhanced antibacterial efficacy. METHODS...
متن کاملFabrication of curcumin-loaded electrospun nanofiberous polyurethanes with anti-bacterial activity
Two series of polyurethane (PU), based on polycaprolactone (PCL) as soft segments with two different molecular weights (2000 and 530 Da), and hexamethylene diisocyanate (HDI) and 1,4-butandiol (BDO) as hard segments were synthesized to fabricate curcumin-loaded electrospun nanofibrous PCL-based PU substrate. Chemical structures of the synthesized PUs were characterized by FTIR and NMR spectrosc...
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ژورنال
عنوان ژورنال: Progress in Biomaterials
سال: 2020
ISSN: 2194-0509,2194-0517
DOI: 10.1007/s40204-020-00140-5